A new study reveals that there is a worrisome association of obesity and metabolic syndrome with breast cancer subtypes and mortality risk.
The findings indicate that MetS and obesity each have different associations with breast cancer subtypes and mortality risk.
After a median follow-up of 23.2 years, there were 4,562 incident breast cancers and 659 deaths from breast cancer (breast cancer mortality),” the study revealed.
Also Read More than one billion people have obesity globally; 160 million children and adolescents affected“Postmenopausal women with higher MetS scores are a previously unrecognized population at higher breast cancer mortality risk.
According to the World Health Organization (WHO), breast cancer caused 670 000 deaths globally in 2022.
A new study reveals that there is a worrisome association of obesity and metabolic syndrome with breast cancer subtypes and mortality risk.
In the Women’s Health Initiative (WHI) randomised trial, a low-fat diet reduced breast cancer mortality, especially in women with more metabolic syndrome (MetS) components which include obesity, high blood pressure, elevated blood sugar, and abnormal cholesterol.
The findings indicate that MetS and obesity each have different associations with breast cancer subtypes and mortality risk. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.
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“The analysis included 63,330 postmenopausal WHI clinical trial participants without prior breast cancer, as well as normal entry mammograms and MetS scores (0–4). After a median follow-up of 23.2 years, there were 4,562 incident breast cancers and 659 deaths from breast cancer (breast cancer mortality),” the study revealed.
The study also highlighted that women with severe obesity for example, a postmenopausal woman 5 feet, 6 inches tall, weighing more than 218 pounds or 98 Kg had a higher risk of breast cancer mortality.
Also Read More than one billion people have obesity globally; 160 million children and adolescents affected
“Postmenopausal women with higher MetS scores are a previously unrecognized population at higher breast cancer mortality risk. Determination of MetS scores in the clinic requires only three questions regarding cholesterol, diabetes, and hypertension history as well as waist circumference and blood pressure measurements, which are commonly determined during routine visits,” said lead author Rowan T. Chlebowski, MD, PhD of The Lundquist Institute.
According to the World Health Organization (WHO), breast cancer caused 670 000 deaths globally in 2022. Meanwhile, 2.3 million women were diagnosed with breast cancer.
